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Common approaches to the management of cervical cancer in pregnancy

Agnieszka Maździarz1, Jerzy Wyględowski1, Anna Skrzypczyk-Ostaszewicz2

Affiliacja i adres do korespondencji
Curr. Gynecol. Oncol. 2014, 12 (4), p. 301–307
DOI: 10.15557/CGO.2014.0029
Streszczenie

Malignancies are rarely diagnosed in pregnant women, yet the increasing age of women getting pregnant contributes to a higher incidence of cancers during this period. Apart from breast cancer, cervical cancer is the most frequently diagnosed malignancy in the said population. The co-occurrence of pregnancy and cancer affects decisions related to diagnostics, treatment, the manner of parturition, the course of the postpartum period and postnatal care. At each stage, the management requires consensus – developed by a multidisciplinary team composed of specialists of different fields: gynecologic oncology, obstetrics, neonatology and oncology. The choice of procedures is also dependent on the patient’s decision regarding the continuation of pregnancy. The majority of reports do not point to any differences in the survival rate between women diagnosed with cervical carcinoma during pregnancy and other women affected by the disease. However, it has been confirmed that pregnancy does not have any effect on the survival time of women affected by invasive cancer. With a broader knowledge of pharmacokinetics of cytostatic drugs administered during pregnancy and new oncologic methods as well as the improvement in the care of a treated mother and fetus, the diagnostic and therapeutic procedures also change. In the case of higher stages of cancer, the latest recommendations suggest the performance of lymphadenectomy in order to assess a high risk of the disease. Is some cases, neoadjuvant chemotherapy is also applied until the fetus reaches its maturity. This paper summarizes the latest scientific reports and recommendations of international expert groups regarding the treatment of cervical cancer during pregnancy.

Słowa kluczowe
cervical cancer, pregnancy, lymphadenectomy, neoadjuvant chemotherapy, cervical dysplasia