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The primary fallopian tube carcinoma – a clinical and morphological analysis of 10 cases

Ryszard Poręba1, Zbigniew Antosz2

Affiliacja i adres do korespondencji
GIN ONKOL, 2005, 3 (3), p. 134-145
Streszczenie

Introduction: Primary carcinoma of the fallopian tube belongs to the rarest malignant neoplasms of the female reproducting organ. The correct preoperative diagnosis is made very rarely. Both clinical symptoms and the results of further examinations do not indicate unequivocally that the cancer is in progress. Therefore, it is recognized intraoperatively and the final diagnosis is given only after histopathological examination. The aim of the paper was to determinate the frequency of the cancer’s occurrence and the age at which it happens as well as to compare the collected data with the literature. Another step was to analyse some information from patient’s history, ginaecological and other extra examinations and to liken them to the results of the histopathological examination in order to find optimal diagnostics. Material and methods: The research involved the material from 10 cases of the primary carcinoma of fallopian tube which were operated on at Clinical Department of Obstetrics and Ginaecology at Silesian Medical Academy in Katowice between 1999-2004. The research took into consideration the age of patients, part of clinical data and histological type as well as the level of it’s grading. The investigation focussed on comparing preoperative diagnosis and changes occurring within the reproducing organ with the results of histopathological examination. That was followed by correlating staging and grading. Results: The results of the research showed that the average age at which the cancer occur is 63. Clinical data suggested the development of the cancer in just one case. The correct preoperative diagnosis was also given in one case. All the patients reported pain complaint. Nevertheless, the positive correlation between grading and staging was not proved. Conclusions: There’s still lack of certain satisfying methods in diagnosing the primary fallopian tube cancer. Hence, it is essential to pay attention to patient’s history with a focus on pain symptoms and their character. Any unsure cases should be verified by histopathological examination with a particular concern about intraoperative examination. There is also postulation for creating Central Register of Primary Fallopian Cancer that would be useful for obtaining epidemiological data and would be inestimable for looking for efficient methods in preoperative diagnostics. What’s more, bigger number of cases will allow to work out standards in diagnostic process.

Słowa kluczowe
primary fallopian tube carcinoma, pain complaint, intraoperative histopathological examination, diagnostic’s indications, Central Registry of Primary Fallopian Cancer